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Category:Disk encryptionA dose-response study of food-derived inflammatory stimuli on dendritic cell function.
A number of dietary factors influence immune function. Inflammatory mechanisms have been associated with the development of allergies and asthma. In vitro exposure of dendritic cells (DCs) to diet-derived molecules may be useful in predicting the effects of dietary triggers of inflammation in vivo. The objective of this study was to determine if macromolecules derived from a number of foods, common to Western diets, could alter the in vitro differentiation of DCs from peripheral blood. In addition, the effect of these foods on cytokine production by DCs was evaluated. We used a series of commercially available foods to explore potential relationships between foods and DC function. Dietary factors were selected for their known effects on DC function. DCs were differentiated in the presence of individual foods and cytokine production was assessed. Dose-response studies showed that foods affected DC function in a variety of ways. The ratio of omega-3 to omega-6 fatty acids in the diet was an important determinant of IL-10 production. The omega-3:omega-6 ratio had a significant effect on IL-12 production and on GM-CSF and IL-4 production from LPS-activated monocytes. The effect of food on DC function may be important in the development of allergies, asthma and atopy.SAE’s road-going R-Model gasoline/petrol hybrid and diesel vehicles have provided a stunning impact on the car industry and have changed the rules of the game. The hybrid car offers higher mileage per gallon than gasoline vehicles and can run on both gasoline and diesel. Diesel and hybrid have changed the face of the automotive industry and now, with advances in technology and infrastructure, SAE's diesel car is expected to see significant growth.
The diesel car will cater to emerging markets, such as India and China and also to the small car segment, such as hatchback cars and two-wheelers. The fuel-efficient vehicle industry is expected to be one of the key growth segments of the auto sector over the next five years.
By an estimate, the diesel engine will be the largest selling engine in the world within the next five years. India is also expected to be the largest diesel car market in the world over the next be359ba680
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